National Cancer Institute   U.S. National Institutes of Health |
Clinical Trials Support Unit


The Children’s Oncology Group (COG) IT department is conducting important maintenance on COG systems on Sunday, August 9, 2020, between 10 am and 3 pm (PT). During this time, COG Patient Registry in OPEN, enrollment, callback and manual treatment assignments will be intermittently unavailable.

Please plan accordingly to ensure business continuity. Note: iMedidata Rave is NOT affected.

Welcome to the Oncology Patient Enrollment Network (OPEN) Portal system

OPEN is the web-based registration system for patient enrollments onto NCI-sponsored Network Group clinical trials. The system is integrated with the CTSU Enterprise System for regulatory and roster data, and with each of the Network Groups' registration/randomization systems for patient registration/ randomization. OPEN provides the ability to enroll patients on a 24/7 basis.

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