National Cancer Institute   U.S. National Institutes of Health |
Clinical Trials Support Unit Oncology Patient Enrollment Network


CTSU Systems staff will be performing monthly maintenance this Saturday, May 28th - OPEN may be unavailable intermittently 8-10 AM. We apologize for any inconvenience this may cause you.

The Children’s Oncology Group (COG) is conducting important maintenance on COG systems on June 2nd from 10:00 am until 12:30pm (PST). No patient reservation, enrollment, callback, manual treatment assignment, study transfers or study data entry for COG studies in OPEN (and eRDES) systems will be available during this time period. Please note that the COG Patient registry in OPEN and iMedidata, Rave are NOT affected.

Please plan accordingly to ensure business continuity during this time period.

Welcome to the Oncology Patient Enrollment Network (OPEN) Portal system

OPEN is the web-based registration system for patient enrollments onto NCI-sponsored Network Group clinical trials. The system is integrated with the CTSU Enterprise System for regulatory and roster data, and with each of the Network Groups' registration/randomization systems for patient registration/ randomization. OPEN provides the ability to enroll patients on a 24/7 basis.

PDF Logo Training and Demonstration Materials:

  • User Guide »This users guide has a linkable Table of Contents that will bring you to any topic you choose, or you can scroll through and/or print the entire guide.
  • OPEN Demo Video »The OPEN training video has been updated and reformatted. Click on one of the tabs at the top of the screen for a drop down list of instructional topics, then click on the specific topic you want to view.
  • Frequently Asked Questions (FAQ) »Frequently asked questions about OPEN Portal.
  • Access & Crediting Guidelines »Guidelines for OPEN Portal Access and Crediting.
  • Slot Reservation Quick User Guide »This user guide is a quick reference intended to assist you with the process of reserving a slot for a patient on protocols that use the slot reservation system.
  • OPEN T&UM Quick Reference Site User Guide »This document provides instructions for using OPEN's Transfer and Update Module to update completed patient enrollments that are maintained in OPEN.

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