National Cancer Institute   U.S. National Institutes of Health |
Clinical Trials Support Unit


On Wednesday, July 15 between 2:00 pm and 3:00 pm (PT), the COG IT department will be conducting system maintenance on the COG RandoNode. Please note the Enrollments on COG studies in OPEN will unavailable during this time. Please plan accordingly to ensure business continuity during this time period.

For questions or concerns, please email the COG Helpdesk at

Welcome to the Oncology Patient Enrollment Network (OPEN) Portal system

OPEN is the web-based registration system for patient enrollments onto NCI-sponsored Network Group clinical trials. The system is integrated with the CTSU Enterprise System for regulatory and roster data, and with each of the Network Groups' registration/randomization systems for patient registration/ randomization. OPEN provides the ability to enroll patients on a 24/7 basis.

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