Clinical Trials Support Unit


On Thursday, August 11 between 9:00 am and 1:00 pm PT/ 12:00 pm to 4:00 pm ET, the COG IT department will be conducting system maintenance on the COG Patients registry in OPEN.

During the maintenance period, please be aware that the following applications will be unavailable:
COG Patients Registry in OPEN including new patient registry creation and registry updates
Enrollments, Step 0 and Callbacks on COG studies in OPEN
eRDES enrollments in COG Member Web site

Note: COG Member Web site and study data entry in iMedidata Rave are not affected.
Please plan accordingly to ensure business continuity during this time period. For questions or concerns, please email the COG Helpdesk at

Welcome to the Oncology Patient Enrollment Network (OPEN) Portal system

OPEN is the web-based registration system for patient enrollments onto NCI-sponsored Network Group clinical trials. The system is integrated with the CTSU Enterprise System for regulatory and roster data, and with each of the Network Groups' registration/randomization systems for patient registration/ randomization. OPEN provides the ability to enroll patients on a 24/7 basis.

PDF Logo Training and Demonstration Materials: